College Football Picks & Predictions This Week

Illinois Fighting Illini at UCLA Bruins: the full matchup breakdown from the Desk.

Houston Cougars at Colorado Buffaloes: the full matchup breakdown from the Desk.

South Carolina Gamecocks at Arkansas Razorbacks: the full matchup breakdown from the Desk.

Florida Gators at Kentucky Wildcats: the full matchup breakdown from the Desk.

North Dakota State should win, but in a 38.5-point game we think Hawai'i +6.5 at +108 is the number worth owning.

Utah State Aggies at San Diego State Aztecs: the full matchup breakdown from the Desk.

UNLV Rebels at New Mexico Lobos: the full matchup breakdown from the Desk.

San José State Spartans at Air Force Falcons: the full matchup breakdown from the Desk.

Southern Miss Golden Eagles at Louisiana Tech Bulldogs: the full matchup breakdown from the Desk.

Fresno State Bulldogs at Texas State Bobcats: the full matchup breakdown from the Desk.

Nevada Wolf Pack at Northern Illinois Huskies: the full matchup breakdown from the Desk.

Florida International Panthers at Delaware Blue Hens: the full matchup breakdown from the Desk.

Kennesaw State Owls at Sam Houston Bearkats: the full matchup breakdown from the Desk.

Tulane Green Wave at Rice Owls: the full matchup breakdown from the Desk.

Wyoming Cowboys at UTEP Miners: the full matchup breakdown from the Desk.

UAB Blazers at Temple Owls: the full matchup breakdown from the Desk.

James Madison Dukes at UConn Huskies: the full matchup breakdown from the Desk.

Stanford Cardinal at Virginia Tech Hokies: the full matchup breakdown from the Desk.

Minnesota Golden Gophers at Penn State Nittany Lions: the full matchup breakdown from the Desk.

California Golden Bears at Virginia Cavaliers: the full matchup breakdown from the Desk.

Kansas State gains more per play than TCU, yet the Horned Frogs are laying 10.5 at home, so we lean Kansas State +10.5 at even money.

Alabama Crimson Tide at Vanderbilt Commodores: the full matchup breakdown from the Desk.

Louisville is the deserved favorite, but the one positive number on the board is North Carolina +3.5 at even money, and that half point is the whole story.

Kansas Jayhawks at West Virginia Mountaineers: the full matchup breakdown from the Desk.

Washington Huskies at Michigan State Spartans: the full matchup breakdown from the Desk.

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Boston College Eagles at Notre Dame Fighting Irish: the full matchup breakdown from the Desk.