LSU vs Tennessee Prediction, Picks & Odds (Nov 21) | WGT
The Wise Guy Desk · College Football
LSU Tigers logo@Tennessee Volunteers logo

LSU vs Tennessee Prediction & Odds (Nov 21)

Quick answer
LSU Tigers vs Tennessee Volunteers starts Sat, Nov 21, 3:30 PM ET at Neyland Stadium. Listed numbers: total 48.5 and moneyline -120 / +118 (away / home). The Desk's lean: LSU -120 (DraftKings), small or pass.
From the numbers on this page, compiled by the Wise Guy Desk. Page content last changed November 12, 2026.
LSU Tigers vs Tennessee Volunteers: No. 24 LSU is a -120 road favorite at No. 9 Tennessee, and our lean is LSU at DraftKings only as a small, nearly break-even play, with a pass the cleaner option. · Neyland Stadium
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Who will win LSU vs Tennessee?

LSU Tigers play at Tennessee Volunteers in college football on Saturday, November 21, at Neyland Stadium. As of 11:14 AM ET, LSU are the moneyline favorite at -120 and the total is 48.5. Prices come from 4 sportsbooks we track. The Desk leans LSU. A prediction is an estimate from the market and the matchup, not a certain result.

Prices updated · from 4 sportsbooks · college football betting splits

Tigers vs Volunteers: line and start time right now

Line
spread Tigers -1.5; total 48.5; moneyline Tigers -135, Volunteers +103 (consensus of 4 sportsbooks) updated
Start
updated
The lean: LSU -120 (DraftKings), small or pass
Total48.5
Moneyline, away / home-120 / +118
KickoffSat, Nov 21, 3:30 PM ET
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Exchange buyers: LSU Tigers at Tennessee Volunteers

Neither Kalshi nor Polymarket has a market on this game that we can match, so there is no exchange buyer data to show.

Polymarket US: prices only

Polymarket US lists moneyline for this game. No trade split yet for these markets (none captured, or too few to show), so they show prices only. Polymarket US is a separate venue from Polymarket (international) and is never added into its numbers.

  • Moneyline: Tigers 51% chance (price only)

LSU Tigers vs Tennessee Volunteers: odds, trends and our lean

📊 Best prices from the regulated US sportsbooks we track Live prices as of 11:14 AM ET · Line shopping can improve your price
MarketLSU TigersTennessee Volunteers
Moneyline-120Bet at DraftKings →+118Bet at FanDuel →
Total 48.5O +100Bet at FanDuel →U -110Bet at DraftKings →

What are the odds for LSU vs Tennessee at each sportsbook?

As of 11:14 AM ET, LSU -120 on the moneyline and the total is 48.5, with 4 sportsbooks priced and the table showing each book's own number.

SportsbookLSU MLTennessee MLLSU spreadTennessee spreadOverUnder
DraftKings-120+100-1.5 -110+1.5 -110O 48.5 -110U 48.5 -110
FanDuel-140+118––O 48.5 +100U 48.5 -120
Fliff-135+105––O 48.5 -110U 48.5 -125
Novig-135-102––––

Prices from 4 sportsbooks we track, updated . Prices move, so check the book before you bet.

📊 Team Breakdown real data · updated daily
Season win %
LSU Tigers
67%
Tennessee Volunteers
78%
Chance to win, per the betting market (vig removed)

Our no-vig fair price on this game is for members. The posted odds are on this page; the fair line, and whether any book is hanging a number worth betting, live in the members' Odds Screen. Start your $1 trial →

Standings & streak
LSU Tigers logoLSU Tigers8th in the Southeastern Conference
Tennessee Volunteers logoTennessee Volunteers5th in the Southeastern Conference
Players to watch
George MacIntyreGeorge MacIntyre (TENN)78/117, 853 YDS, 2 TD, 3 INT (7 GP)
Sam LeavittSam Leavitt (LSU)215/303, 2,553 YDS, 17 TD, 9 INT (9 GP)
How to read this: "chance to win per the betting market" comes from the actual odds with the sportsbook's built-in fee (the vig) stripped out, the market's honest opinion of the game.
🛈 Wise Guy Desk analysis - not an official play. A free breakdown to help you find value and bet the best number. Ross's documented plays are graded win or loss on the members board.
📘 New to betting? Two-minute translation. A moneyline bet is picking who wins, nothing else. In this game, +118 means a $100 bet profits $118 if it wins. The spread is a head start: -7.5 must win by 8+, while +7.5 cashes by losing by 7 or fewer (or winning). The total is combined points by both teams, over or under the books' number. +EV means the price pays better than the market-implied fair odds (vig removed); consistently taking better prices raises your expected return over time. Learn free: Sports Betting 101 · Odds converter · No-vig calculator

Prices are posted now. Best prices as of 11:14 AM ET: LSU Tigers -120 at DraftKings, Tennessee Volunteers +118 at FanDuel. The full best-price table sits at the top of this page.

Tennessee vs LSU Prediction: A Top-10 Team as a Home Underdog

The No. 9 team in the country is an underdog in its own building. The LSU Tigers, ranked No. 24, are -120 favorites at the Tennessee Volunteers. Kickoff is Saturday, November 21, 2026 at 3:30 PM ET at Neyland Stadium in Week 12. The gap between the poll and the price drives this whole LSU vs Tennessee preview. So who does the market trust, and should you pay for that trust?

The Matchup: Who Is Favored to Win LSU vs Tennessee?

As of November 12, LSU is 6-3 and sits 8th of 16 in the Southeastern Conference. Tennessee is 7-2 and 5th. The AP poll (week 11) has Tennessee ninth and LSU 24th. The books still favor LSU, and the deeper ratings show why. Elo, a rating that rises and falls after every result, has LSU at 1898 and Tennessee at 1879. Predicted points added per play (PPA) measures how much each snap helps a team score. Higher is better on offense.

More negative is better on defense. Over nine games each, LSU sits at 0.22 on offense and -0.07 on defense. Tennessee is at 0.19 and -0.08. These are two very similar teams, with LSU slightly sharper with the ball. Last season's final SP+ (an efficiency rating we treat only as a preseason starting point) had Tennessee at 15 and LSU at 10.3. One more market note: LSU's championship price fell from 11.1 percent implied to 5.4 percent over eight days.

Players to Watch

Sam Leavitt is LSU's passing leader over all nine games: 215 of 303 for 2,553 yards, 17 touchdowns and 9 interceptions. Per game, that is 283.7 yards, 1.9 touchdowns and 1 interception. George MacIntyre leads Tennessee in passing over seven of the team's nine games: 78 of 117 for 853 yards, 2 touchdowns and 3 interceptions. Per game, that is 121.9 yards, 0.3 touchdowns and 0.4 interceptions. They have played different numbers of games, so the per-game figures are the fair comparison. LSU's passing game is clearly the bigger weekly engine. Tennessee's 0.19 offensive PPA says the Volunteers still move the ball efficiently overall.

The Numbers: LSU vs Tennessee Odds and Spread

The moneyline is a bet on who wins outright. LSU at -120 (best at DraftKings) means a $100 bet profits $83.33 if LSU wins. You need LSU to win 54.5% of the time just to break even. Tennessee at +118 (best at FanDuel) means $100 profits $118.00, with a break-even of 45.9%. Books build in a fee called the vig.

Strip it out and the market reads LSU at about 54.5% and Tennessee at about 45.5%. LSU is the favorite, Tennessee the underdog. The total is 48.5 combined points. Over and Under are both -110 at DraftKings: $100 profits $90.91, break-even 52.4%. Those listed prices are the best across books. Shopping gets you there.

Where the Value Is

Expected value is your average result per bet if you could make the same bet many times. That is nearly break-even, but still negative. Nothing here clears break-even.

The Pick

Our honest read is a pass on any full-size bet. Keep it small, and do not lay worse than -120. This is Wise Guy Desk analysis, not an official play.

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The Prediction

Our LSU vs Tennessee prediction: LSU 24, Tennessee 21. That adds to 45 points, under the 48.5 total. We still would not bet the Under at -110 given its minus $4.55 expectation. LSU's efficiency and per-game passing edge carry a close one on the road. That is the read on this number; the Desk posts a documented free play on days like this, and it lands right below.

LSU vs Tennessee FAQ

Who is favored in LSU vs Tennessee?

LSU is the market favorite at -120 (best price at DraftKings) on the moneyline, with Tennessee at +118. Lines move all day, so check the odds table on this page for the current best number at every book.

Who is favored to win LSU vs Tennessee?

The LSU Tigers are the favorite at -120 on the moneyline (best at DraftKings), and the Tennessee Volunteers are the underdog at +118 (best at FanDuel). With the vig removed, the market reads LSU at about 54.5% and Tennessee at about 45.5%, even though Tennessee is ranked higher in the AP poll.

What time is the LSU vs Tennessee game?

LSU at Tennessee kicks off Saturday, November 21, 2026 at 3:30 PM Eastern time at Neyland Stadium. It is a Week 12 game of the 2026 regular season, with the Tennessee Volunteers hosting the LSU Tigers.

What are the LSU vs Tennessee odds and total?

LSU is -120 at DraftKings and Tennessee is +118 at FanDuel on the moneyline. The total is 48.5 points, with both the Over and Under at -110 at DraftKings. The sportsbooks we track had not posted a point spread for this game at publication.

Who will win Tennessee vs LSU?

No. 24 LSU is a -120 road favorite at No. 9 Tennessee, and our lean is LSU at DraftKings only as a small, nearly break-even play, with a pass the cleaner option. The full read, including a projected final score, is in The Prediction section above.

What is the total (over/under) for LSU vs Tennessee?

The total is 48.5, with the over priced at +100 at FanDuel and the under at -110 at DraftKings. A total is a bet on the combined score of both teams, over or under that number, no matter who wins.

Are these College Football picks free?

Yes. This is a free Wise Guy Desk breakdown, our analysis, not Ross's official plays. Ross's documented plays are bet with real money and graded win or loss on the members board.

How does the Wise Guy Desk find value in College Football games?

Expected value first: the best price across the regulated US books we track versus the true fair price with the vig removed, then the matchup data (form, standings, injuries, key players). Line shopping for the best number is the edge most bettors leave on the table.

This preview was produced with AI assistance from live data feeds and reviewed by automated checks. Odds and availability change constantly and may differ from what's shown - always verify the current line at your sportsbook before betting. Found an error? memberservice@wiseguyteam.com.
21+. For entertainment and educational purposes, not financial advice. Wise Guy Desk reads are analysis, not guaranteed outcomes. If gambling stops being fun, take a break. 1-800-GAMBLER.

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