Buccaneers vs Lions Prediction, Picks & Odds (Nov 22) | WGT
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Tampa Bay Buccaneers logo@Detroit Lions logo

Buccaneers vs Lions Prediction & Odds (Nov 22)

Quick answer
Tampa Bay Buccaneers vs Detroit Lions starts Sun, Nov 22, 1:00 PM ET at Ford Field. Listed numbers: spread Lions -3.5, total 47.5 and moneyline +155 / -172 (away / home). The Desk's lean: Lions ML -190 (FanDuel). Injury report: DET Kerby Joseph (Out) and 4 more; TB Yaya Diaby (Out) and 4 more.
From the numbers on this page, compiled by the Wise Guy Desk. Page content last changed November 13, 2026.
Tampa Bay Buccaneers vs Detroit Lions: Every price on this board costs you something, but the Detroit Lions moneyline at -190 on FanDuel costs the least, so that is our small lean at Ford Field. ยท Ford Field

Who will win Buccaneers vs Lions?

Tampa Bay Buccaneers play at Detroit Lions in the NFL on Sunday, November 22, at Ford Field. As of 1:44 AM ET, Lions are 3.5-point favorites and the total is 47.5. Prices come from 9 sportsbooks we track. The Desk leans Lions ML. A prediction is an estimate from the market and the matchup, not a certain result.

Prices updated · from 9 sportsbooks · NFL betting splits

Buccaneers vs Lions: line, injuries and start time right now

Latest since this preview was written: Amon-Ra St. Brown (DET) now questionable, was active (5:44 PM ET); Cade Mays (DET) now out, was questionable (5:44 PM ET); D.J. Reed (DET) now out, was questionable (5:44 PM ET); and 6 more changes.

Line
spread Lions -3.5; total 47.5; moneyline Buccaneers +150, Lions -180 (consensus of 9 sportsbooks) updated
Buccaneers injuries
Antoine Winfield Jr. questionable, Jalen McMillan on injured reserve, Yaya Diaby out updated
Lions injuries
Amon-Ra St. Brown questionable, Cade Mays out, D.J. Reed out, Isiah Pacheco on injured reserve, Jack Campbell on injured reserve, Jimmy Rolder on injured reserve, Kerby Joseph out, Sione Vaki questionable updated
Start
updated
The lean: Lions ML -190 (FanDuel)
SpreadLions -3.5
Total47.5
Moneyline, away / home+155 / -172
KickoffSun, Nov 22, 1:00 PM ET
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Exchange buyers: Tampa Bay Buccaneers at Detroit Lions

Neither Kalshi nor Polymarket has a market on this game that we can match, so there is no exchange buyer data to show.

Polymarket US: prices only

Polymarket US lists moneyline for this game. No trade split yet for these markets (none captured, or too few to show), so they show prices only. Polymarket US is a separate venue from Polymarket (international) and is never added into its numbers.

  • Moneyline: Buccaneers 38% chance (price only)

Tampa Bay Buccaneers vs Detroit Lions: odds, trends and our lean

๐Ÿ“Š Best prices from the regulated US sportsbooks we track Live prices as of 1:44 AM ET ยท Line shopping can improve your price
MarketTampa Bay BuccaneersDetroit Lions
Moneyline+155betPARX-172Bet at FanDuel →
Spread+3.5 -113betPARX-3.5 +100Bet at FanDuel →
Total 47.5O -110Bet at DraftKings →U -110Bet at DraftKings →

What are the odds for Buccaneers vs Lions at each sportsbook?

As of 1:44 AM ET, the spread is Lions -3.5 and the total is 47.5, with 9 sportsbooks priced and the table showing each book's own number.

SportsbookBuccaneers MLLions MLBuccaneers spreadLions spreadOverUnder
Bally Bet+155-190+3.5 -113-3.5 -108O 47.5 -110U 47.5 -110
bet365+150-180+3.5 -118-3.5 -102O 47.5 -110U 47.5 -110
betPARX+155-190+3.5 -113-3.5 -108O 47.5 -110U 47.5 -110
BetRivers+155-190+3.5 -113-3.5 -108O 47.5 -110U 47.5 -110
Caesars+149-176+3.5 -114-3.5 -106O 47.5 -110U 47.5 -110
DraftKings+150-180+3.5 -115-3.5 -105O 47.5 -110U 47.5 -110
FanDuel+144-172+3.5 -120-3.5 +100O 47.5 -110U 47.5 -110
Novig+150-178+3.5 -122-3.5 -108––
ReBet+145-180––O 47.5 -110U 47.5 -110

Prices from 9 sportsbooks we track, updated . Prices move, so check the book before you bet.

๐Ÿ“Š Team Breakdown real data ยท updated daily
Season win %
Tampa Bay Buccaneers
33%
Detroit Lions
75%
Chance to win, per the betting market (vig removed)

Our no-vig fair price on this game is for members. The posted odds are on this page; the fair line, and whether any book is hanging a number worth betting, live in the members' Odds Screen. Start your $1 trial →

Standings & streak
Tampa Bay Buccaneers logoTampa Bay Buccaneers3rd in the NFC South
Detroit Lions logoDetroit Lions2nd in the NFC North
Players to watch
Jared GoffJared Goff (DET)185/273, 2,134 YDS, 15 TD, 2 INT (8 GP)
Baker MayfieldBaker Mayfield (TB)86/142, 922 YDS, 3 TD, 4 INT (6 GP)
How to read this: "chance to win per the betting market" comes from the actual odds with the sportsbook's built-in fee (the vig) stripped out, the market's honest opinion of the game.
๐Ÿ›ˆ Wise Guy Desk analysis - not an official play. A free breakdown to help you find value and bet the best number. Ross's documented plays are graded win or loss on the members board.
๐Ÿ“˜ New to betting? Two-minute translation. A moneyline bet is picking who wins, nothing else. In this game, +155 means a $100 bet profits $155 if it wins. The spread is a head start: -7.5 must win by 8+, while +7.5 cashes by losing by 7 or fewer (or winning). The total is combined points by both teams, over or under the books' number. +EV means the price pays better than the market-implied fair odds (vig removed); consistently taking better prices raises your expected return over time. Learn free: Sports Betting 101 ยท Odds converter ยท No-vig calculator

Buccaneers vs Lions: Every Price Has a Cost

Every single price on this game carries negative expected value, from the favorite to the underdog to both sides of the total. Then add a Tampa Bay quarterback who is listed Active in one injury report and Out in another. This Buccaneers vs Lions matchup is a test of discipline more than a test of nerve. The Tampa Bay Buccaneers visit the Detroit Lions at Ford Field on Sunday, November 22, 2026, at 1:00 PM ET on Fox. It is Week 11.

The Matchup

As of November 10, the Lions are 6-2 and sit 2nd of 4 in the NFC North. The Buccaneers are 3-6, 3rd of 4 in the NFC South. Those records are from publication day, and more football gets played before kickoff. Our data shows no earlier meeting between these teams this season, so there is no season series to lean on. Lions vs Buccaneers comes down to the matchup in front of us and the price.

Players to Watch

Jared Goff has played all eight Detroit games: 185 of 273 for 2,134 yards, 15 touchdowns and 2 interceptions. Per game, that is 266.8 yards, 1.9 touchdowns and 0.3 interceptions. Baker Mayfield has played six of Tampa Bay's nine games: 86 of 142 for 922 yards, 3 touchdowns and 4 interceptions. Per game, that is 153.7 yards, 0.5 touchdowns and 0.7 interceptions. In Tampa Bay's last game, tight end Cade Otton played 100% of offensive snaps, Chris Godwin 92% and Emeka Egbuka 86%. Amon-Ra St. Brown is listed Active for Detroit.

Who Is Favored to Win Buccaneers vs Lions?

Detroit is favored. The moneyline is a bet on who wins outright. Lions -190 at FanDuel means you risk $100 to profit $52.63. Buccaneers +164 at DraftKings means a $100 bet profits $164.00. The point spread is a margin bet. Tampa Bay +3.5 at -105 (DraftKings) wins if Tampa Bay wins outright or loses by 3 or fewer. It loses on a 4-point loss. Detroit -3.5 at -110 (Caesars) wins only if Detroit wins by 4 or more.

There is no push (tie bet) at a half point. The total is a bet on combined points: Over 47.5 at -109 (ReBet), Under 47.5 at -110 (DraftKings). Those are the best prices we found, and shopping across books is value left on the table if you skip it. Books build in a fee called the vig. Strip it out and the market reads Detroit 64% and Tampa Bay 36%.

Where the Value Is

Break-even is how often a bet must win to stop losing money. Expected value is your average result per $100 risked over many bets, not what you win on any one ticket. Tampa Bay +164 needs 37.9% but the market reads 36.2%, an average of minus $4.41. Detroit -190 needs 65.5% against 63.8%, minus $2.64. Tampa Bay +3.5 needs 51.2% against a 49.7% cover read, minus $3.06. Detroit -3.5 needs 52.4% against 50.3%, minus $3.88. The Over sits at minus $4.13 and the Under at minus $4.55. Nothing here is positive. The smallest drag per $100 risked is the Detroit moneyline.

Is Baker Mayfield Playing? Injuries

The reports conflict. One ESPN report lists Mayfield Active, while another lists him Out with a thumb injury. Antoine Winfield Jr. is listed Questionable in one report and Out with a rib injury in another. Yaya Diaby is Out, and Jalen McMillan, Josh Hayes and Christian Rozeboom are on injured reserve. For Detroit, Kerby Joseph, DJ Wonnum, D.J. Reed, Jacob Saylors and Cade Mays are listed Out, though another ESPN report shows Wonnum, Reed and Mays Questionable. Isiah Pacheco and Jack Campbell are on injured reserve. Final designations come later in the week, before Sunday's kickoff.

The Pick

Our lean is the Detroit Lions moneyline at -190 on FanDuel. Be clear on what this is. A 6-2 home team against a 3-6 visitor with quarterback uncertainty is the read. Passing is a perfectly sharp choice here.

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The Prediction

Our Lions vs Buccaneers prediction: Detroit Lions 27, Tampa Bay Buccaneers 20. That adds up to 47 points, just under the 47.5 total, though we would not bet the total at these prices. We see Goff steady at home and Tampa Bay's passing game held in check, but the price tells us not to overpay for that view. That is the read on this number. The Desk posts a documented free play on days like this, and it lands right below.

Injury Report

DETKerby Joseph (Out), DJ Wonnum (Out), D.J. Reed (Out), Jacob Saylors (Out), Cade Mays (Out)
TBYaya Diaby (Out), Antoine Winfield Jr. (Questionable), Jalen McMillan (Injured Reserve), Josh Hayes (Injured Reserve), Christian Rozeboom (Injured Reserve)

Buccaneers vs Lions FAQ

Who is favored in Buccaneers vs Lions?

Lions is the market favorite at -172 (best price at FanDuel) on the moneyline, with Buccaneers at +155. Lines move all day, so check the odds table on this page for the current best number at every book.

Where to watch Buccaneers vs Lions?

The Tampa Bay Buccaneers at Detroit Lions game airs on Fox. Kickoff is Sunday, November 22, 2026, at 1:00 PM ET at Ford Field in Week 11 of the regular season.

What time is the Buccaneers vs Lions game?

The game kicks off Sunday, November 22, 2026, at 1:00 PM Eastern time. It is played at Ford Field and broadcast on Fox.

Who is favored to win Buccaneers vs Lions?

The Detroit Lions are favored. The best moneyline prices we track are Lions -190 at FanDuel and Buccaneers +164 at DraftKings. The spread is Lions -3.5, and with the vig removed the market reads Detroit at 64% and Tampa Bay at 36%.

Who will win Lions vs Buccaneers?

Every price on this board costs you something, but the Detroit Lions moneyline at -190 on FanDuel costs the least, so that is our small lean at Ford Field. The full read, including a projected final score, is in The Prediction section above.

What is the total (over/under) for Buccaneers vs Lions?

The total is 47.5, with the over priced at -110 at DraftKings and the under at -110 at DraftKings. A total is a bet on the combined score of both teams, over or under that number, no matter who wins.

Are these NFL picks free?

Yes. This is a free Wise Guy Desk breakdown, our analysis, not Ross's official plays. Ross's documented plays are bet with real money and graded win or loss on the members board.

How does the Wise Guy Desk find value in NFL games?

Expected value first: the best price across the regulated US books we track versus the true fair price with the vig removed, then the matchup data (form, standings, injuries, key players). Line shopping for the best number is the edge most bettors leave on the table.

Quick answers

Who is starting at quarterback in Tampa Bay Buccaneers vs Detroit Lions?

Depth chart starters: Tampa Bay Buccaneers Baker Mayfield, Detroit Lions Jared Goff.

Who is injured for Tampa Bay Buccaneers vs Detroit Lions?

Tampa Bay Buccaneers: David Sills (out), SirVocea Dennis (questionable), Benjamin Morrison (doubtful), Ayden Garnes (questionable).

As of Nov 10, 11:47 PM ET, when this preview was written. Percentages are public betting splits and market prices, not picks.

This preview was produced with AI assistance from live data feeds and reviewed by automated checks. Odds and availability change constantly and may differ from what's shown - always verify the current line at your sportsbook before betting. Found an error? memberservice@wiseguyteam.com.
21+. For entertainment and educational purposes, not financial advice. Wise Guy Desk reads are analysis, not guaranteed outcomes. If gambling stops being fun, take a break. 1-800-GAMBLER.

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