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Jacksonville Jaguars play at New York Giants in the NFL on Sunday, November 22, at MetLife Stadium. As of 1:50 AM ET, Jaguars are 6-point favorites and the total is 44.5. Prices come from 9 sportsbooks we track. The Desk leans Jaguars ML. A prediction is an estimate from the market and the matchup, not a certain result.
Prices updated · from 9 sportsbooks · NFL betting splits
Latest since this preview was written: J.C. Davis (NYG) now out, was not listed (11:54 PM ET); Jason Pinnock (NYG) now questionable, was not listed (11:54 PM ET); Josh Sills (NYG) now out, was not listed (11:54 PM ET); and 4 more changes.
Neither Kalshi nor Polymarket has a market on this game that we can match, so there is no exchange buyer data to show.
| Market | Jacksonville Jaguars | New York Giants |
|---|---|---|
| Moneyline | -217Bet at Polymarket → exchange price | +215Bet at DraftKings → |
| Spread | -6 -110Bet at DraftKings → | +6 -107Bet at Bally Bet → |
| Total 44.5 | O -110Bet at DraftKings → | U -105Bet at FanDuel → |
As of 1:50 AM ET, the spread is Jaguars -6 and the total is 44.5, with 9 sportsbooks priced and the table showing each book's own number.
| Sportsbook | Jaguars ML | Giants ML | Jaguars spread | Giants spread | Over | Under |
|---|---|---|---|---|---|---|
| Bally Bet | -245 | +195 | -6 -114 | +6 -107 | O 44.5 -110 | U 44.5 -110 |
| betPARX | -245 | +195 | -6 -114 | +6 -107 | O 44.5 -110 | U 44.5 -110 |
| BetRivers | -245 | +195 | -6 -114 | +6 -107 | O 44.5 -110 | U 44.5 -110 |
| DraftKings | -265 | +215 | -6 -110 | +6 -110 | O 44.5 -110 | U 44.5 -110 |
| bet365 | -265 | +215 | – | – | O 44.5 -112 | U 44.5 -108 |
| FanDuel | -260 | +215 | – | – | O 44.5 -115 | U 44.5 -105 |
| Novig | -233 | +194 | – | – | O 44.5 -122 | U 44.5 -113 |
| ReBet | -265 | +208 | – | – | O 44.5 -110 | U 44.5 -110 |
| Circa | – | – | -6 -110 | +6 -110 | – | – |
Prices from 9 sportsbooks we track, updated . Prices move, so check the book before you bet.
Our no-vig fair price on this game is for members. The posted odds are on this page; the fair line, and whether any book is hanging a number worth betting, live in the members' Odds Screen. Start your $1 trial →
Jacksonville Jaguars1st in the AFC SouthNew York Giants1st in the NFC East
Jameis Winston (NYG)96/166, 1,028 YDS, 8 TD, 5 INT (8 GP)
Trevor Lawrence (JAX)146/224, 1,932 YDS, 18 TD, 4 INT (8 GP)Two first-place teams meet at MetLife Stadium, and the market treats only one of them like a contender. The Jacksonville Jaguars are -245 favorites on the road, while the New York Giants sit at +215 at home. That gap is the story of this Week 11 game. The bettor's question is simple: is the favorite worth that price? Kickoff is Sunday, November 22 at 4:25 PM ET on CBS.
As of November 14, the Jaguars are 6-2 and first of four in the AFC South. The Giants are 5-3-1 (the 1 is a tie) and first of four in the NFC East. They play in different conferences, so there is no season series to lean on. The Jaguars are the clear favorite. The futures market likes them too. Their Super Bowl price moved from 9.1 percent to 11.8 percent implied probability over eight days. Implied probability is the win chance a price suggests.
Trevor Lawrence has played all eight Jaguars games. Over those eight games he averages 241.5 passing yards, 2.3 touchdowns and 0.5 interceptions per game (18 TD, 4 INT total). Jameis Winston has played eight of the Giants' nine games. Over those eight he averages 128.5 passing yards, 1 touchdown and 0.6 interceptions per game (8 TD, 5 INT total). The sample is equal and the output is not. Lawrence is throwing for nearly twice the yards per game. That gap goes a long way toward explaining why the Jaguars odds look the way they do.
The moneyline is a bet on who wins, nothing else. A minus sign marks the favorite and a plus sign marks the underdog. Jaguars -245 at Bally Bet means a $100 bet profits $40.82. Giants +215 at DraftKings means a $100 bet profits $215. Those are the best Giants odds and Jaguars odds we track.
The spread adds points to even things out. Jaguars -6 at -110 (DraftKings) wins only if the Jaguars win by 7 or more. A 6-point win is a push, which means your stake comes back, and a 5-point win loses. Giants +6 at -107 (Bally Bet) wins if the Giants win outright or lose by 5 or fewer. The -110 and -107 are the cost of the bet: you risk $110 or $107 to profit $100. That extra cost is the vig, the book's fee.
The total is 44.5 combined points. The Over is best at -110 on DraftKings and the Under at -105 on FanDuel. The best prices are spread across three different books, and that is the whole case for shopping. A few cents saved on every bet adds up.
Take the vig out and the market reads this about 70.6% Jaguars, 29.4% Giants. Break-even is the win rate a bet needs to stop losing money over time. Jaguars -245 needs 71%. Expected value is your average result if you could make the same bet many times. To be clear, nothing on this board is positive. By the market's own read, the Jaguars moneyline at Bally Bet is the smallest negative.
The Giants are listed without four players: Malik Harrison, Nikko Reed, Josh Sills and defensive tackle CJ Okoye. Jason Pinnock is questionable, which means his status is uncertain. The Jaguars are listed without Jessie Bates III and Cam'Ron Silmon-Craig. Defensive end B.J. Green II and Eric Murray are on injured reserve, and Robert Hainsey is questionable. Check the final inactives before kickoff on Sunday.
Jaguars moneyline at -245 at Bally Bet. That makes it a lean on the better team and the better quarterback, not an edge. If you play it, keep it small and take only the best number. A worse price elsewhere only deepens the hole.
Our Giants vs Jaguars read comes down to the quarterbacks. Lawrence's per-game production over eight games separates these offenses, and Winston's 128.5 yards per game over eight games has not shown it can keep pace. Our Jaguars vs Giants prediction is Jaguars 24, Giants 17. That adds up to 41 points, under the 44.5 total. That is the Desk's read on this number. The documented free daily play sits right below if you want to see how we handle a full card.
Jaguars is the market favorite at -217 (best price at Polymarket) on the moneyline, with Giants at +215. Lines move all day, so check the odds table on this page for the current best number at every book.
The Jacksonville Jaguars at New York Giants game airs on CBS. Kickoff is Sunday, November 22, 2026 at 4:25 PM ET from MetLife Stadium in Week 11 of the regular season.
The Jacksonville Jaguars are the favorite at -245 (best at Bally Bet), and the New York Giants are the underdog at +215 (best at DraftKings). With the vig removed, the market reads it about 70.6% Jaguars to 29.4% Giants. The Jaguars are also 6-point favorites on the spread.
The Jaguars vs Giants game kicks off Sunday, November 22, 2026 at 4:25 PM Eastern time at MetLife Stadium. It is a Week 11 regular-season game broadcast on CBS.
Jacksonville Jaguars vs New York Giants NFL prediction, picks and best bet from the Wise Guy Desk. The full read, including a projected final score, is in The Prediction section above.
The total is 44.5, with the over priced at -110 at DraftKings and the under at -105 at FanDuel. A total is a bet on the combined score of both teams, over or under that number, no matter who wins.
Yes. This is a free Wise Guy Desk breakdown, our analysis, not Ross's official plays. Ross's documented plays are bet with real money and graded win or loss on the members board.
Expected value first: the best price across the regulated US books we track versus the true fair price with the vig removed, then the matchup data (form, standings, injuries, key players). Line shopping for the best number is the edge most bettors leave on the table.
More for this game: NFL public betting splits · DraftKings betting splits · NFL odds · FanDuel betting splits
Depth chart starters: Jacksonville Jaguars Trevor Lawrence, New York Giants Jameis Winston.
Jacksonville Jaguars: Alijah Huzzie (active), Ameer Abdullah (active), Antonio Johnson (active), B.J. Green II (injured reserve); New York Giants: Abdul Carter (active), Ar'Darius Washington (active), Arvell Reese (active), Bryan Hudson (active).
As of Nov 14, 7:48 AM ET, when this preview was written. Percentages are public betting splits and market prices, not picks.
This preview was produced with AI assistance from live data feeds and reviewed by automated checks. Odds and availability change constantly and may differ from what's shown - always verify the current line at your sportsbook before betting. Found an error? memberservice@wiseguyteam.com.
21+. For entertainment and educational purposes, not financial advice. Wise Guy Desk reads are analysis, not guaranteed outcomes. If gambling stops being fun, take a break. 1-800-GAMBLER.